Publications at VCU
20) Develin A, Fuglestad B. Inositol Hexaphosphate as an Inhibitor and Potential Regulator of p47phox Membrane Anchoring. Biochemistry, published online ahead of print.
19) Mahmoud R, Kalivarathan J, Castillo AJ, Wang S, Fuglestad B, Kanak MA, Dhakal S. Aptabinding of tumor necrosis factor-α (TNFα) inhibits its proinflammatory effects and alleviates islet inflammation. Biotechnol J. 2024 Jan;19(1):e2300374.
18) Walters SH, Castillo AJ, Develin AM, Labrecque CL, Qu Y, Fuglestad B. Investigating protein-membrane interactions using native reverse micelles constructed from naturally sourced lipids. Protein Sci. 2023 Sep 25:e4786. (Featured on the Front Cover)
17) Labrecque CL, Nolan AL, Develin AM, Castillo AJ, Offenbacher AR, Fuglestad B. Membrane-Mimicking Reverse Micelles for High-Resolution Interfacial Study of Proteins and Membranes. Langmuir, 2022 Mar 29;38(12):3676-3686. (Featured on the Front Cover)
16) Labrecque CL, Fuglestad B. Electrostatic Drivers of GPx4 Interactions with Membrane, Lipids, and DNA. Biochemistry, 2021 Sep 7;60(37): 2761-2772.
Pre-VCU publications
15) MacKenzie DW, Schaefer A, Steckner J, Leo CA, Naser D, Artikis E, Broom A, Ko T, Shah P, Ney MQ, Tran E, Smith MTJ, Fuglestad B, Wand AJ, Brooks III CL, Meiering EM. A fine balance of hydrophobic-electrostatic communication pathways in a pH-switching protein. Proc Natl Acad Sci U S A. 2022, 119(26), e2119686119.
14) O'Brien ES, Fuglestad B, Lessen HJ, Stetz MA, Lin DW, Marques BS, Gupta K, Fleming KG, Wand AJ. Membrane Proteins Have Distinct Fast Internal Motion and Residual Conformational Entropy. Angew Chem Int Ed Engl. 2020, 59, 11108-11114
13) Fuglestad B, Kerstetter NE, Bedard S, Wand AJ. Extending the Detection Limit in Fragment Screening of Proteins using Reverse Micelle Encapsulation. ACS Chem. Biol. 2019 Oct 18;14(10): 2224-2232
12) Fuglestad B, Kerstetter NE, and Wand, AJ. Site-resolved and quantitative characterization of very weak protein-ligand interactions. ACS Chem. Biol. 2019 Jul 19;14(7):1398-1402.
11) Fuglestad B, Gupta K, Wand AJ, Sharp KA. Water loading driven size, shape, and composition of cetyltrimethylammonium/hexanol/pentane reverse micelles. J Colloid Interface Sci. 2019 Mar 22;540:207-217.
10) Fuglestad B, Marques BS, Jorge C, Kerstetter NE, Valentine KG, Wand AJ. Reverse micelle encapsulation of proteins for NMR spectroscopy. Methods Enzymol. 2019;615:43-75.
9) O'Brien ES, Lin DW, Fuglestad B, Stetz MA, Gosse T, Tommos C, Wand AJ. Improving yields of deuterated, methyl labeled protein by growing in H2O. J Biomol NMR. 2018 Aug;71(4):263-273.
8) Fuglestad B, Stetz MA, Belnavis Z, Wand AJ. Solution NMR investigation of the response of the lactose repressor core domain dimer to hydrostatic pressure. Biophys Chem. 2017 Dec;231:39-44.
7) Handley LD*, Fuglestad B*, Stearns K, Tonelli M, Fenwick RB, Markwick PR, Komives EA. NMR reveals a dynamic allosteric pathway in thrombin. Sci Rep. 2017 Jan 6;7:39575.
6) Fuglestad B, Gupta K, Wand AJ, Sharp KA. Characterization of cetyltrimethylammonium bromide/hexanol reverse micelles by experimentally benchmarked molecular dynamics simulations. Langmuir. 2016 Feb 23;32(7):1674-84.
5) O'Brien ES, Nucci NV, Fuglestad B, Tommos C, Wand AJ. Defining the Apoptotic Trigger: the interaction of cytochrome c and cardiolipin. J Biol Chem. 2015 Dec 25;290(52):30879-87.
4) Nucci NV, Fuglestad B, Athanasoula EA, Wand AJ. Role of cavities and hydration in the pressure unfolding of T4 lysozyme. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13846-51.
3) Fuglestad B*, Gasper PM*, McCammon JA, Markwick PR, Komives EA. Correlated motions and residual frustration in thrombin. J Phys Chem B. 2013 Oct 24;117(42):12857-63.
2) Gasper PM, Fuglestad B, Komives EA, Markwick PR, McCammon JA. Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21216-22.
1) Fuglestad B, Gasper PM, Tonelli M, McCammon JA, Markwick PR, Komives EA. The dynamic structure of thrombin in solution. Biophys J. 2012 Jul 3;103(1):79-88.
*Denotes equal contribution